SAPHNELO® 300mg/2ml (International English)
$3,799.00
SAPHNELO® 300 mg/2 ml is a biologic prescription medicine containing anifrolumab‑fnia, a human monoclonal antibody that targets the type I interferon receptor to help reduce immune system overactivity in adults with moderate to severe systemic lupus erythematosus (SLE) who are already receiving standard therapy. It is supplied as a 300 mg/2 ml (150 mg/ml) single‑dose vial for intravenous infusion given by a healthcare professional, typically over 30 minutes every four weeks. Studies have shown that SAPHNELO plus standard care can significantly reduce lupus disease activity compared with standard care alone.
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Description
Key Product Insights:
- Contains anifrolumab‑fnia, a human monoclonal antibody targeting type I interferon receptor.
- Indicated as an add‑on treatment for moderate to severe systemic lupus erythematosus (SLE) in adults under standard therapy.
- 300 mg/2 mL (150 mg/mL) vial for intravenous infusion administered by a healthcare professional.
- Works by blocking type I interferon signaling, reducing immune activation and inflammation.
- Given as a 30‑minute IV infusion every 4 weeks.
- Clinical trials showed reduced disease activity and steroid usage versus placebo.
- Most common side effects include upper respiratory infections, bronchitis, infusion reactions, and shingles.
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